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Article

A genetic method for dissecting the mechanism of transcriptional activator synergy by identical activators.

Proceedings of the National Academy of Sciences of the United States of America - 26 Oct 1999

Langdon R C, Hochschild A

Abstract excerpt

Pairs of transcriptional activators in prokaryotes have been shown to activate transcription synergistically from promoters with two activator binding sites. In some cases, such synergistic effects result from cooperative binding, but in other cases each DNA-bound activator plays a direct role in the activation process by interacting simultaneously with separate surfaces of RNA polymerase. In such cases, each...

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Identifiers

PMID: 10535981
DOI: 10.1073/pnas.96.22.12673
PMCID: PMC23043

Genes

CRP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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