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Article

Pancreatic expression of B7 co-stimulatory molecules in the non-obese diabetic mouse.

International immunology - 1 Dec 1995

Stephens L A, Kay T W

Abstract excerpt

Expression of the co-stimulatory molecule B7-1 (CD80) on pancreatic beta cells can overcome peripheral T cell tolerance in transgenic models of autoimmune disease. This study aimed to determine if aberrant B7-1 or B7-2 (CD86) expression on pancreatic beta cells is involved in the pathogenesis of...

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Source

Identifiers

PMID: 8746558
DOI: 10.1093/intimm/7.12.1885

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8746558-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Pancreatic expression of B7 co-stimulatory molecules in the non-obese diabetic mouse.PMID 8746558Read ↗

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Islet-infiltrating t lymphocytes in insulin-dependent diabetic patients express CD80 (B7-1) and CD86 (B7-2).Semantic proximity Read ↗

A crucial role of CD4 T cells as a functional source of CD154 in the initiation of insulin-dependent diabetes mellitus in the non-obese diabetic mouse.Semantic proximity Read ↗

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Reduction in diabetes incidence in an I-Ag7 transgenic nonobese diabetic mouse line.Semantic proximity Read ↗

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