Article
Is lack of peripheral tolerance induction a cause for diabetes in the non-obese diabetic mouse?
Archivum immunologiae et therapiae experimentalis - 1 Jan 2000
Lund T, Strid J
Abstract excerpt
The non-obese diabetic (NOD) mouse is a spontaneous animal model for type 1 diabetes characterized by a selective destruction of the insulin producing beta cells in the pancreas. As in humans, the disease is controlled by several susceptibility genes, some of which map to the major histocompatibi...
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