Article
The importance of the 3' untranslated region for the expression of the alpha-globin genes.
Hemoglobin - 1 Feb 1996
Molchanova T P, Huisman T H
Abstract excerpt
With a reverse transcription-polymerase chain reaction procedure, we have determined the relative quantities of alpha 2- and alpha 1-mRNA in several patients with heterozygosities for alpha 2- or alpha 1-globin gene mutations, in subjects with two forms of alpha-thalassemia-2 (-3.7 kb; -4.2 kb),...
Topics
- Gene Deletion
- Gene Expression
- Genetic Variation
- Globins
- Humans
- Multigene Family
- Protein Biosynthesis
- RNA, Messenger