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Article

The differences in quantities of alpha 2- and alpha 1-globin gene variants in heterozygotes.

British journal of haematology - 1 Oct 1994

Molchanova T P, Pobedimskaya D D, Huisman T H

Abstract excerpt

We have identified through sequencing of amplified DNA the mutations in the alpha 2- and alpha 1-globin genes in 63 individuals with a heterozygosity for an alpha chain abnormal haemoglobin (Hb). Moreover, we developed a reverse transcription/polymerase chain reaction (RT/PCR) based procedure for the determination of the alpha 2- and alpha 1-mRNA ratio in normal individuals. The numbers of alpha 2 and alpha 1...

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Source

Identifiers

PMID: 7803274
DOI: 10.1111/j.1365-2141.1994.tb05022.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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