Article
Erythroid cell-specific mRNA stability elements in the alpha 2-globin 3' nontranslated region.
Molecular and cellular biology - 1 May 1995
Weiss I M, Liebhaber S A
Abstract excerpt
Very little is known about the mechanisms mediating longevities of mRNAs. As a means of identifying potential cis- and trans-acting elements which stabilize an individual mRNA, naturally occurring mutations that decreased stability of the normally long-lived globin mRNA were analyzed. Our previou...
Topics
- Animals
- Base Sequence
- DNA Primers
- Drug Stability
- Erythrocytes
- Globins
- Humans
- Leukemia, Erythroblastic, Acute
- Mice
- Models, Biological
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation
- Protein Biosynthesis
- RNA, Messenger
- Tumor Cells, Cultured