Article
Erythroid cell-specific mRNA stability elements in the alpha 2-globin 3' nontranslated region.
Molecular and cellular biology - 1 May 1995
Weiss I M, Liebhaber S A
Abstract excerpt
Very little is known about the mechanisms mediating longevities of mRNAs. As a means of identifying potential cis- and trans-acting elements which stabilize an individual mRNA, naturally occurring mutations that decreased stability of the normally long-lived globin mRNA were analyzed. Our previous studies demonstrated that a subset of mutations which allowed the translating ribosome to read through into the alpha...
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