Article
Attenuated hippocampal damage after global cerebral ischemia in mice mutant in neuronal nitric oxide synthase.
Neuroscience - 1 May 1996
Panahian N, Yoshida T, Huang P L, Hedley-Whyte E T, Dalkara T, Fishman M C, Moskowitz M A
Abstract excerpt
To address the importance of nitric oxide or its reaction products as mediators of neurotoxicity in brain, tissue injury was assessed after transient global ischemia in mice rendered mutant in the gene for neuronal nitric oxide synthase. Halothane-anesthetized wild type and mutant mice were subje...
Topics
- Animals
- Brain Ischemia
- Carbon
- Gene Expression Regulation, Enzymologic
- Hippocampus
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Inbred Strains
- Mutation
- Neurons
- Nitric Oxide Synthase