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Article

Rapid cerebral ischemic preconditioning in mice deficient in endothelial and neuronal nitric oxide synthases.

Stroke - 1 May 2003

Atochin Dmitriy N, Clark Jeffrey, Demchenko Ivan T, Moskowitz Michael A, Huang Paul L

Abstract excerpt

BACKGROUND AND PURPOSE: The purpose of this study was to test the hypothesis that nitric oxide is required for preconditioning in an intact animal model of focal ischemia using neuronal and endothelial nitric oxide synthase (nNOS and eNOS) knockout mice. METHODS: Cerebral blood flow was measured in wild-type, nNOS knockout, and eNOS knockout mice by hydrogen clearance (absolute) and laser Doppler flowmetry...

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Source

Identifiers

PMID: 12677017
DOI: 10.1161/01.STR.0000066870.70976.57

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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