'Fingerprinting' of HLA-DQA by polymerase chain reaction and heteroduplex analysis.

doi:10.1006/mcpr.1996.0017

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Article

'Fingerprinting' of HLA-DQA by polymerase chain reaction and heteroduplex analysis.

Molecular and cellular probes - 1 Apr 1996

Martinelli G, Trabetti E, Farabegoli P, Buzzi M, Zaccaria A, Testoni N, Amabile M, Casartelli A, de Vivo A, Pignatti P F, Tura S

Abstract excerpt

We have developed a rapid, non-radioisotopic PCR fingerprinting technique for analysis of the HLA-Class II DQA gene second exon polymorphism, and have applied it to DNA samples from 210 healthy individuals. The technique is based on the formation of specific patterns (fingerprints) of homoduplexe...

Topics

Alleles
DNA
DNA Fingerprinting
Genes, MHC Class II
Genetic Carrier Screening
HLA-DQ Antigens
HLA-DQ alpha-Chains
Homozygote
Humans
Nucleic Acid Heteroduplexes
Polymerase Chain Reaction
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 8737396
DOI: 10.1006/mcpr.1996.0017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8737396-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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