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Article

Rapid typing of HLA-DQB1 DNA polymorphism using nonradioactive oligonucleotide probes and amplified DNA.

Immunogenetics - 1 Jan 1991

Bugawan T L, Erlich H A

Abstract excerpt

The allelic sequence diversity at the HLA-DQB1 locus has been analyzed by polymerase chain reaction (PCR) amplification and sequencing. Fifteen amino acid sequence-defined alleles (one previously unreported) and several silent nucleotide polymorphisms which subdivide these alleles have been identified. Here, we describe the specific amplification of the DQB1 second exon by several different PCR primer pairs and a...

Topics

Alleles
Amino Acid Sequence
Base Sequence
HLA-DQ Antigens
HLA-DQ beta-Chains
Humans
Molecular Sequence Data
Oligonucleotide Probes
Polymerase Chain Reaction
Polymorphism, Genetic

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Identifiers

PMID: 2010218
DOI: 10.1007/BF01719235

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2010218-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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