Article
HLA-DQ alpha allele and genotype frequencies in various human populations, determined by using enzymatic amplification and oligonucleotide probes.
American journal of human genetics - 1 Sept 1990
Helmuth R, Fildes N, Blake E, Luce M C, Chimera J, Madej R, Gorodezky C, Stoneking M, Schmill N, Klitz W
Abstract excerpt
Allele and genotype frequencies at the HLA-DQ alpha locus have been determined by the use of polymerase chain reaction (PCR) amplification and nonradioactive oligonucleotide probes. The probes define six alleles and 21 genotypes in a dot-blot format. A total of over 1,400 individuals from 11 popu...
Topics
- Alleles
- Base Sequence
- Gene Frequency
- Genetic Variation
- Genotype
- HLA-DQ Antigens
- Humans
- Molecular Sequence Data
- Oligonucleotide Probes
- Polymerase Chain Reaction