Article
HLA class II genotyping: two assay systems compared.
Clinical chemistry - 1 Apr 1995
Thonnard J, Deldime F, Heusterspreute M, Delepaut B, Hanon F, De Bruyère M, Philippe M
Abstract excerpt
In the last few years, a variety of DNA-based human leukocyte antigen (HLA) typing methods have emerged, revealing the extreme polymorphism of HLA genes. This polymorphism makes it difficult for a clinical laboratory to establish the best HLA typing strategy. In this study we have compared two te...
Topics
- Alleles
- Genotype
- Histocompatibility Antigens Class II
- Humans
- Nucleic Acid Hybridization
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Sensitivity and Specificity
- Temperature