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Article

Phenotypic modification of primary sensory neurons: the role of nerve growth factor in the production of persistent pain.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 29 Mar 1996

Woolf C J

Abstract excerpt

Inflammation results in an early and maintained elevation in nerve growth factor (NGF) levels in inflamed tissues. Neutralizing the action of the increased NGF with specific anti-NGF antibodies substantially diminishes inflammatory hypersensitivity, indicating that this neurotrophin is a key mediator in the production of inflammatory pain. The hyperalgesic actions of NGF may in part be the consequence of an...

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Source

Identifiers

PMID: 8730783
DOI: 10.1098/rstb.1996.0040

Genes

NGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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