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Article

Differentiation of the 50B11 dorsal ganglion cells into NGF and GDNF responsive nociceptor subtypes.

Molecular pain - 1 Jan 2000

Dusan Matusica, Jastrow Canlas, Alyce Martin M, Yingkai Wei, Shashikanth Marri, Andelain Erickson, Christine Barry M, Stuart Brierley M, Oliver Best G, Michael Michael Z, Nicolas Voelcker H, Damien Keating J, Rainer Haberberger V

Abstract excerpt

The embryonic rat dorsal root ganglion (DRG) neuron-derived 50B11 cell line is a promising sensory neuron model expressing markers characteristic of NGF and GDNF-dependent C-fibre nociceptors. Whether these cells have the capacity to develop into distinct nociceptive subtypes based on NGF- or GDNF-dependence has not been investigated. Here we show that by augmenting forskolin (FSK) and growth factor...

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Identifiers

PMID: 33307981
DOI: 10.1177/1744806920970368
PMCID: PMC7745567

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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