Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

No association of the structural dopamine D2 receptor (DRD2) variant 311Cys with alcoholism.

Alcoholism, clinical and experimental research - 1 May 1996

Finckh U, von Widdern O, Giraldo-Velasquez M, Podschus J, Dufeu P, Sander T, Harms H, Schmidt L G, Rommelspacher H, Rolfs A

Abstract excerpt

The human dopamine D2 receptor (DRD2) has been implied in the vulnerability for alcoholism and/or the modification of its severity. This is supported through animal experimental and pharmacological data. We analyzed the DRD2 311Ser/Cys polymorphism in 312 German alcoholics and 131 ethnically matched controls to investigate the association of genetic DRD2 variants with alcoholism or clinical characteristics of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Cysteine

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Gene Frequency

Share to Genetic Variation

Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 8727249
DOI: 10.1111/j.1530-0277.1996.tb01087.x

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

No association of the structural dopamine D2 receptor (DRD2) variant 311Cys with alcoholism.PMID 8727249Read ↗

Functional variant in the DRD2 receptor promoter region and subtypes of alcoholism.Semantic proximity Read ↗

A functionally deficient DRD2 variant [Ser311Cys] is not linked to alcoholism and substance abuse.Semantic proximity Read ↗

Reappraisal of the association between the DRD2 gene, alcoholism and addiction.Semantic proximity Read ↗

Association of the -141C Del variant of the dopamine D2 receptor (DRD2) with positive family history and suicidality in German alcoholics.Semantic proximity Read ↗

Association of structural polymorphism of the dopamine D2 receptor gene and alcoholism.Semantic proximity Read ↗

Dopamine D2 receptor gene (DRD2) haplotypes in Caucasians.Semantic proximity Read ↗

Lack of an allelic association between polymorphisms of the dopamine D2 receptor gene and alcohol dependence in the German population.Semantic proximity Read ↗

Association and family studies of DRD2 gene polymorphisms in alcohol dependence syndrome.Semantic proximity Read ↗

Linkage and association of a functional DRD2 variant [Ser311Cys] and DRD2 markers to alcoholism, substance abuse and schizophrenia in Southwestern American Indians.Semantic proximity Read ↗

A structural polymorphism of human dopamine D2 receptor, D2(Ser311-->Cys).Semantic proximity Read ↗

Predominant influence of the 3'-region of dopamine D2 receptor gene (DRD2) on the clinical phenotype in German alcoholics.Semantic proximity Read ↗

Family-based and case-control study of DRD2, DAT, 5HTT, COMT genes polymorphisms in alcohol dependence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.