Article
Lack of an allelic association between polymorphisms of the dopamine D2 receptor gene and alcohol dependence in the German population.
Alcoholism, clinical and experimental research - 1 Apr 1999
Sander T, Ladehoff M, Samochowiec J, Finckh U, Rommelspacher H, Schmidt L G
Abstract excerpt
Our study examined recent claims of an association of the TaqI A1 allele and the functional -141C Ins allele of the dopamine D2 receptor (DRD2) gene with alcohol dependence. Genotypes of the TaqI A and -141C insertion/deletion polymorphisms were assessed in 196 German nonalcoholic controls and 310 German alcohol-dependent subjects, including two more homogeneous subgroups selected by either a history of parental...
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