Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Family-based and case-control study of DRD2, DAT, 5HTT, COMT genes polymorphisms in alcohol dependence.

Neuroscience letters - 13 Dec 2006

Samochowiec Jerzy, Kucharska-Mazur Jolanta, Grzywacz Anna, Jabłoński Marcin, Rommelspacher Hans, Samochowiec Agnieszka, Sznabowicz Mariusz, Horodnicki Jan, Sagan Leszek, Pełka-Wysiecka Justyna

Abstract excerpt

The paper focuses on such candidate gene polymorphisms that alter alcoholism-related intermediate phenotypes including: dopaminergic system polymorphic variants (DRD2 -141C Ins/Del in promoter region, exon 8 and DRD2 TaqI A and DAT 40bp VNTR genes polymorphisms) that cause predisposition to severe alcoholism (haplotype Ins/G/A2); COMT Val158Met gene polymorphism related to differences in executive cognitive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcoholism
Share to Catechol O-Methyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dopamine Plasma Membrane Transport Proteins

Share to Methionine

Share to Minisatellite Repeats

Share to Receptors, Dopamine D2

Share to Serotonin Plasma Membrane Transport Proteins

Share to Valine

Source

Identifiers

PMID: 17079080
DOI: 10.1016/j.neulet.2006.05.005

Genes

DRD2
COMT
HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Family-based and case-control study of DRD2, DAT, 5HTT, COMT genes polymorphisms in alcohol dependence.PMID 17079080Read ↗

Association and family studies of DRD2 gene polymorphisms in alcohol dependence syndrome.Semantic proximity Read ↗

Population-based case-control study of DRD2 gene polymorphisms and alcoholism.Semantic proximity Read ↗

Serotonin and Dopamine Candidate Gene Variants and Alcohol- and Non-Alcohol-Related Aggression.Semantic proximity Read ↗

Association of the -141C Del variant of the dopamine D2 receptor (DRD2) with positive family history and suicidality in German alcoholics.Semantic proximity Read ↗

Association of the dopamine D2 receptor gene with alcohol dependence: haplotypes and subgroups of alcoholics as key factors for understanding receptor function.Semantic proximity Read ↗

Associated and intermediate factors between genetic variants of the dopaminergic D2 receptor gene and harmful alcohol use in young adults.Semantic proximity Read ↗

[Genetic factors in alcohol dependence].Semantic proximity Read ↗

Association of gene polymorphisms encoding dopaminergic system components and platelet MAO-B activity with alcohol dependence and alcohol dependence-related phenotypes.Semantic proximity Read ↗

Predominant influence of the 3'-region of dopamine D2 receptor gene (DRD2) on the clinical phenotype in German alcoholics.Semantic proximity Read ↗

Influence of Dopaminergic System Genetic Variation and Lifestyle Factors on Excessive Alcohol Consumption.Semantic proximity Read ↗

[Case-control, family based and screening for DNA sequence variation in the dopamine transporter gene polymorphism DAT 1 in alcohol dependence].Semantic proximity Read ↗

The DRD2 gene in psychiatric and neurological disorders and its phenotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.