Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Linkage and association of a functional DRD2 variant [Ser311Cys] and DRD2 markers to alcoholism, substance abuse and schizophrenia in Southwestern American Indians.

American journal of medical genetics - 25 Jul 1997

Goldman D, Urbanek M, Guenther D, Robin R, Long J C

Abstract excerpt

Alcoholism is one of a group of common psychiatric diseases which are well-defined clinically and strongly influenced genetically, but which are likely to be highly heterogeneous in causation, genetically and otherwise. Dopamine is a key neurotransmitter in drug-mediated reinforcement. Based on a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Disease Susceptibility
Share to Ethnicity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Genotype

Share to Haplotypes

Share to Linkage Disequilibrium

Share to Point Mutation

Source

Identifiers

PMID: 9259374
DOI: 10.1002/(sici)1096-8628(19970725)74:4<386::aid-ajmg9>3.0.co;2-n

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9259374-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Linkage and association of a functional DRD2 variant [Ser311Cys] and DRD2 markers to alcoholism, substance abuse and schizophrenia in Southwestern American Indians.PMID 9259374Read ↗

A functionally deficient DRD2 variant [Ser311Cys] is not linked to alcoholism and substance abuse.Semantic proximity Read ↗

Association of structural polymorphism of the dopamine D2 receptor gene and alcoholism.Semantic proximity Read ↗

Dopamine D2 receptor gene Ser311Cys variant and schizophrenia: association study and meta‐analysisSemantic proximity Read ↗

Dopamine D2 receptor polymorphisms and susceptibility to alcohol dependence in Indian males: a preliminary study.Semantic proximity Read ↗

Association of the -141C Del variant of the dopamine D2 receptor (DRD2) with positive family history and suicidality in German alcoholics.Semantic proximity Read ↗

The Cys allele of the DRD2 Ser311Cys polymorphism has a dominant effect on risk for schizophrenia: evidence from fixed- and random-effects meta-analyses.Semantic proximity Read ↗

Advanced research on dopamine signaling to develop drugs for the treatment of mental disorders: Ser311Cys polymorphisms of the dopamine D2-receptor gene and schizophrenia.Semantic proximity Read ↗

No association of the structural dopamine D2 receptor (DRD2) variant 311Cys with alcoholism.Semantic proximity Read ↗

Association between Ser311Cys polymorphism in the dopamine D2 receptor gene and schizophrenia risk: a meta-analysis in Asian populations.Semantic proximity Read ↗

Functional variant in the DRD2 receptor promoter region and subtypes of alcoholism.Semantic proximity Read ↗

Association of DRD2 gene variant with schizophrenia.Semantic proximity Read ↗

No major role for the dopamine D2 receptor Ser-->Cys311 mutation in schizophrenia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.