Article
Functional variant in the DRD2 receptor promoter region and subtypes of alcoholism.
American journal of medical genetics - 12 Jun 2000
Parsian A, Cloninger C R, Zhang Z H
Abstract excerpt
Dopaminergic pathway genes are considered as candidate genes for several neuropsychiatric diseases including severe alcoholism. Since 1990, there have been numerous reports of conflicting association studies of the Taq I A allele of the dopamine D2 receptor (DRD2) gene and alcoholism. Functional and structural variations in candidate genes offer more direct evaluation of their role in the development of a...
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