Article
Association of structural polymorphism of the dopamine D2 receptor gene and alcoholism.
Biochemical and biophysical research communications - 15 Nov 1994
Higuchi S, Muramatsu T, Murayama M, Hayashida M
Abstract excerpt
To examine the possible association between three recently identified structural polymorphisms of the dopamine D2 receptor (DRD2) gene and alcoholism, we compared allele frequencies of these polymorphisms in 280 Japanese alcoholics and 289 normal controls. The results revealed that only one of th...
Topics
- Age of Onset
- Alcoholism
- Alleles
- Amino Acid Sequence
- Base Sequence
- Cysteine
- DNA Primers
- Exons
- Female
- Genetic Carrier Screening
- Homozygote
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Point Mutation
- Polymerase Chain Reaction
- Polymorphism, Genetic