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Article

Association of structural polymorphism of the dopamine D2 receptor gene and alcoholism.

Biochemical and biophysical research communications - 15 Nov 1994

Higuchi S, Muramatsu T, Murayama M, Hayashida M

Abstract excerpt

To examine the possible association between three recently identified structural polymorphisms of the dopamine D2 receptor (DRD2) gene and alcoholism, we compared allele frequencies of these polymorphisms in 280 Japanese alcoholics and 289 normal controls. The results revealed that only one of three variants identified in white individuals existed in the alcoholic and control Japanese. The frequency of the Cys311...

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Source

Identifiers

PMID: 7980596
DOI: 10.1006/bbrc.1994.2590

Genes

DRD2

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of structural polymorphism of the dopamine D2 receptor gene and alcoholism.PMID 7980596Read ↗

Association of dopamine D2 receptor molecular variant with schizophrenia.Semantic proximity Read ↗

Linkage and association of a functional DRD2 variant [Ser311Cys] and DRD2 markers to alcoholism, substance abuse and schizophrenia in Southwestern American Indians.Semantic proximity Read ↗

A structural polymorphism of human dopamine D2 receptor, D2(Ser311-->Cys).Semantic proximity Read ↗

Association between Ser311Cys polymorphism in the dopamine D2 receptor gene and schizophrenia risk: a meta-analysis in Asian populations.Semantic proximity Read ↗

No association of the structural dopamine D2 receptor (DRD2) variant 311Cys with alcoholism.Semantic proximity Read ↗

A functionally deficient DRD2 variant [Ser311Cys] is not linked to alcoholism and substance abuse.Semantic proximity Read ↗

No major role for the dopamine D2 receptor Ser-->Cys311 mutation in schizophrenia.Semantic proximity Read ↗

No association of dopamine D2 receptor molecular variant Cys311 and schizophrenia in Chinese patients.Semantic proximity Read ↗

Association study between the -141C Ins/Del and TaqI A polymorphisms of the dopamine D2 receptor gene and alcoholism.Semantic proximity Read ↗

Genetic polymorphisms of the promoter region of dopamine D2 receptor and dopamine transporter genes and alcoholism among four aboriginal groups and Han Chinese in Taiwan.Semantic proximity Read ↗

Dopamine D2 receptor gene Ser311Cys variant and schizophrenia: association study and meta‐analysisSemantic proximity Read ↗

Association of the -141C Del variant of the dopamine D2 receptor (DRD2) with positive family history and suicidality in German alcoholics.Semantic proximity Read ↗

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