Article
Dopamine D2 receptor gene (DRD2) haplotypes in Caucasians.
Gene - 14 Nov 1996
Finckh U, Giraldo-Velasquez M, Pelz J, Otto G, Sander T, Schmidt L G, Rommelspacher H, Rolfs A
Abstract excerpt
The human dopamine D2 receptor gene (DRD2) is considered a candidate gene for neuro-psychiatric diseases. We typed three new DNA sequence variants in DRD2 intron 4, intron 6 and exon 8, in combination with the known TaqI A restriction fragment length polymorphism (RFLP) and exon 7 311Ser/Cys in 106 unrelated psychiatrically healthy Caucasians. Based on the genotypic data we delineated 10 distinct DRD2 haplotypes...
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