Article
Systematic screening for mutations in the human serotonin 1F receptor gene in patients with bipolar affective disorder and schizophrenia.
American journal of medical genetics - 9 Apr 1996
Shimron-Abarbanell D, Harms H, Erdmann J, Albus M, Maier W, Rietschel M, Körner J, Weigelt B, Franzek E, Sander T, Knapp M, Propping P, Nöthen M M
Abstract excerpt
Using single strand conformational analysis we screened the complete coding sequence of the serotonin 1F (5-HT1F) receptor gene for the presence of DNA sequence variation in a sample of 137 unrelated individuals including 45 schizophrenic patients, 46 bipolar patients, as well as 46 healthy controls. We detected only three rare sequence variants which are characterized by single base pair substitutions, namely a...
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