Article
Investigation of the human serotonin 6 [5-HT6] receptor gene in bipolar affective disorder and schizophrenia.
American journal of medical genetics - 3 Apr 2000
Vogt I R, Shimron-Abarbanell D, Neidt H, Erdmann J, Cichon S, Schulze T G, Müller D J, Maier W, Albus M, Borrmann-Hassenbach M, Knapp M, Rietschel M, Propping P, Nöthen M M
Abstract excerpt
Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter that mediates a wide range of central nervous functions by activating multiple 5-HT receptor subtypes. A possible irregularity of serotonergic neurotransmission has been implicated in a variety of neuropsychiatric diseases. In the present study, we performed a systematic mutation scan of the complete coding region and splice junctions of the 5-HT(6)...
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