Article
Lack of genetically determined structural variants of the human serotonin-1E (5-HT1E) receptor protein points to its evolutionary conservation.
Brain research. Molecular brain research - 1 Apr 1995
Shimron-Abarbanell D, Nöthen M M, Erdmann J, Propping P
Abstract excerpt
Using single strand conformational analysis, we screened the complete coding sequence of the serotonin-1E (5-HT1E) receptor gene for the presence of DNA sequence variation in a sample of 157 unrelated individuals. We detected only a silent C-->T transition at the third position of codon 177. The...
Topics
- Base Sequence
- Biological Evolution
- Case-Control Studies
- Humans
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Receptors, Serotonin
