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Article

Maternal inheritance and chromosome 18 allele sharing in unilineal bipolar illness pedigrees.

American journal of medical genetics - 9 Apr 1996

Gershon E S, Badner J A, Detera-Wadleigh S D, Ferraro T N, Berrettini W H

Abstract excerpt

We have replicated the observation of McMahon et al. [1995] that there is excess maternal transmission of illness in a series of previously described unilineal Bipolar manic-depressive illness extended pedigrees [Berrettini et al., 1991]. ("Transmission" is defined for any ill person in a pedigree when father or mother has a personal or immediate family history of major affective disorder.) We divided our...

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PMID: 8723048
DOI: 10.1002/(SICI)1096-8628(19960409)67:2<202::AID-AJMG11>3.0.CO;2-N

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