Article
Do multiple data sets provide support for a bipolar illness susceptibility locus on chromosome 18?
Genetic epidemiology - 1 Jan 1997
Daly M, Kirby A, Kruglyak L
Abstract excerpt
We carried out nonparametric linkage (NPL) analysis of the five chromosome 18 data sets for bipolar illness, as well as of the combined data set. Prior to analysis, we constructed a common genetic map and computed separate marker allele frequencies for each data set. We also attempted to create two consistent diagnostic categories, Narrow (bipolar I, BPI, only) and Broad. The results of the analysis of the...
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