Article
Mitochondrial genetic analyses suggest selection against maternal lineages in bipolar affective disorder.
American journal of human genetics - 1 Aug 1999
Kirk R, Furlong R A, Amos W, Cooper G, Rubinsztein J S, Walsh C, Paykel E S, Rubinsztein D C
Abstract excerpt
Previous reports of preferential transmission of bipolar affective disorder (BP) from the maternal versus the paternal lines in families suggested that this disorder may be caused by mitochondrial DNA mutations. We have sequenced the mitochondrial genome in 25 BP patients with family histories of...
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