Article
Irish study on high-density schizophrenia families: field methods and power to detect linkage.
American journal of medical genetics - 9 Apr 1996
Kendler K S, O'Neill F A, Burke J, Murphy B, Duke F, Straub R E, Shinkwin R, Ni Nuallain M, MacLean C J, Walsh D
Abstract excerpt
Large samples of multiplex pedigrees will probably be needed to detect susceptibility loci for schizophrenia by linkage analysis. Standardized ascertainment of such pedigrees from culturally and ethnically homogeneous populations may improve the probability of detection and replication of linkage. The Irish Study of High-Density Schizophrenia Families (ISHDSF) was formed from standardized ascertainment of...
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