Support for a possible schizophrenia vulnerability locus in region 5q22-31 in Irish families.

doi:10.1038/sj.mp.4000258

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Article

Support for a possible schizophrenia vulnerability locus in region 5q22-31 in Irish families.

Molecular psychiatry - 1 Mar 1997

Straub R E, MacLean C J, O'Neill F A, Walsh D, Kendler K S

Abstract excerpt

In our genome scan for schizophrenia genes in 265 Irish pedigrees, marker D5S818 in 5q22 produced the second best result of the first 223 markers tested (P = 0.002). We then tested an additional 13 markers and the evidence suggests the presence of a vulnerability locus for schizophrenia in region...

Topics

Chromosomes, Human, Pair 5
Chromosomes, Human, Pair 6
Chromosomes, Human, Pair 8
Disease Susceptibility
Female
Genetic Heterogeneity
Genotype
Humans
Ireland
Lod Score
Male
Models, Genetic
Pedigree
Schizophrenia

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