Article
Genomewide linkage scan of schizophrenia in a large multicenter pedigree sample using single nucleotide polymorphisms.
Molecular psychiatry - 1 Aug 2009
Holmans P A, Riley B, Pulver A E, Owen M J, Wildenauer D B, Gejman P V, Mowry B J, Laurent C, Kendler K S, Nestadt G, Williams N M, Schwab S G, Sanders A R, Nertney D, Mallet J, Wormley B, Lasseter V K, O'Donovan M C, Duan J, Albus M, Alexander M, Godard S, Ribble R, Liang K Y, Norton N, Maier W, Papadimitriou G, Walsh D, Jay M, O'Neill A, Lerer F B, Dikeos D, Crowe R R, Silverman J M, Levinson D F
Abstract excerpt
A genomewide linkage scan was carried out in eight clinical samples of informative schizophrenia families. After all quality control checks, the analysis of 707 European-ancestry families included 1615 affected and 1602 unaffected genotyped individuals, and the analysis of all 807 families included 1900 affected and 1839 unaffected individuals. Multipoint linkage analysis with correction for marker-marker linkage...
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