Article
Complementation mapping of skeletal and central nervous system abnormalities in mice of the piebald deletion complex.
Genetics - 1 May 1996
O'Brien T P, Metallinos D L, Chen H, Shin M K, Tilghman S M
Abstract excerpt
The s15DttMb, s36Pub, s1Acrg and s24Pub piebald deletion alleles belong to a set of overlapping deficiencies on the distal portion of chromosome 14. Molecular analysis was used to define the extent of the deletions. Mice homozygous for the smallest deletion, s15DttMb, die shortly after delivery a...
Topics
- Abnormalities, Multiple
- Alleles
- Animals
- Animals, Newborn
- Base Sequence
- Brain
- Chromosome Deletion
- Chromosome Mapping
- Crosses, Genetic
- DNA Primers
- Female
- Fetus
- Genetic Complementation Test
- Genetic Markers
- Genotype
- Heterozygote
- Homozygote
- Hydrocephalus