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Article

Fine structure mapping and deletion analysis of the murine piebald locus.

Genetics - 1 Jan 1994

Metallinos D L, Oppenheimer A J, Rinchik E M, Russell L B, Dietrich W, Tilghman S M

Abstract excerpt

piebald (s) is a recessive mutation that affects the development of two cell types of neural crest origin: the melanocytes, responsible for pigment synthesis in the skin, and enteric ganglia, which innervate the lower bowel. As a result, mice carrying piebald mutations exhibit white spotting in t...

Topics

Animals
Base Sequence
Chromosome Mapping
Crosses, Genetic
DNA
DNA Primers
Female
Genes, Recessive
Genetic Linkage
Genetic Markers
Hair Color
Homozygote
Liver

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Megacolon

Mice

Mice, Mutant Strains

Molecular Sequence Data

Source

Open in PubMed Open full text

Identifiers

PMID: 8138159
DOI: 10.1093/genetics/136.1.217
PMCID: PMC1205773

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8138159-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Fine structure mapping and deletion analysis of the murine piebald locus.PMID 8138159Read ↗

Quantitative trait loci that modify the severity of spotting in piebald mice.Semantic proximity Read ↗

Molecular and functional mapping of the piebald deletion complex on mouse chromosome 14.Semantic proximity Read ↗

Complementation mapping of skeletal and central nervous system abnormalities in mice of the piebald deletion complex.Semantic proximity Read ↗

Piebald lethal (sl) acts early to disrupt the development of neural crest-derived melanocytes.Semantic proximity Read ↗

Molecular characterization of four induced alleles at the Ednrb locus.Semantic proximity Read ↗

An essential gene mutagenesis screen across the highly conserved piebald deletion region of mouse chromosome 14.Semantic proximity Read ↗

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Dominant negative and loss of function mutations of the c-kit (mast/stem cell growth factor receptor) proto-oncogene in human piebaldism.Semantic proximity Read ↗

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