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Article

Fine structure mapping and deletion analysis of the murine piebald locus.

Genetics - 1 Jan 1994

Metallinos D L, Oppenheimer A J, Rinchik E M, Russell L B, Dietrich W, Tilghman S M

Abstract excerpt

piebald (s) is a recessive mutation that affects the development of two cell types of neural crest origin: the melanocytes, responsible for pigment synthesis in the skin, and enteric ganglia, which innervate the lower bowel. As a result, mice carrying piebald mutations exhibit white spotting in the coat and aganglionic megacolon. Previously the gene had been localized to the distal half of mouse chromosome 14. To...

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Identifiers

PMID: 8138159
DOI: 10.1093/genetics/136.1.217
PMCID: PMC1205773

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Fine structure mapping and deletion analysis of the murine piebald locus.PMID 8138159Read ↗

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