Article
Processing of eukaryotic pre-rRNA: the role of the transcribed spacers.
Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Jan 2000
van Nues R W, Venema J, Rientjes J M, Dirks-Mulder A, Raué H A
Abstract excerpt
The 17-18S, 5.8S, and 25-28S rRNA species of eukaryotic cells are produced by a series of nucleolytic reactions that liberate the mature rRNAs from the large primary precursor transcript synthesized by RNA polymerase 1. Whereas the order of the cleavage reactions has long been established, until recently little information was available on their molecular details, such as the nature of the proteins, including the...
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