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Ribosomal RNA processing in Candida albicans

25 Oct 2011

Abstract excerpt

Ribosome assembly begins with conversion of a polycistronic precursor into 18S, 5.8S, and 25S rRNAs. In the ascomycete fungus Candida albicans, rRNA transcription starts 604 nt upstream of the 18S rRNA junction (site A1). One major internal processing site in the 5' external transcribed spacer (A0) occurs 108 nt from site A1. The A0-A1 fragment persists as a stable species during log phase growth and can be used...

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PMID: 22028364
DOI: 10.1261/rna.028050.111

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