Isolation and characterization of murine vav2, a member of the vav family of proto-oncogenes.

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Article

Isolation and characterization of murine vav2, a member of the vav family of proto-oncogenes.

Oncogene - 18 Jul 1996

Schuebel K E, Bustelo X R, Nielsen D A, Song B J, Barbacid M, Goldman D, Lee I J

Abstract excerpt

We describe the isolation and characterization of a cDNA encoding murine vav2. vav2 shares 63% and 55% identity at the nucleic acid and amino acid levels, respectively, with vav, a proto-oncogene that plays an essential role in embryonic development and hematopoietic signal transduction. The 100...

Topics

3T3 Cells
Amino Acid Sequence
Animals
Base Sequence
Cell Transformation, Neoplastic
Cloning, Molecular
DNA, Complementary
Gene Expression Regulation
Gene Expression Regulation, Developmental
Gene Expression Regulation, Neoplastic
Mice
Molecular Sequence Data
Mutation
Neoplasms, Experimental
Oncogene Proteins
Proto-Oncogene Proteins c-vav
Rats
Sequence Homology, Amino Acid

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Open in PubMed

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PMID: 8710375

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8710375-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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