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Article

The haematopoietic specific signal transducer Vav1 is expressed in a subset of human neuroblastomas

11 Feb 2003

Abstract excerpt

Vav1 is a signal transducer protein expressed exclusively in the haematopoietic system, where it plays a pivotal role in growth factor-induced differentiation and proliferation. Vav1 couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, leading to cell differentiation and/or proliferation. Vav1 was originally detected as an oncogene, but its involvement in human malignancies has not been...

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PMID: 12635144
DOI: 10.1002/path.1314

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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The haematopoietic specific signal transducer Vav1 is expressed in a subset of human neuroblastomasPMID 12635144Read ↗

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