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Article

Major transcript variants of VAV3, a new member of the VAV family of guanine nucleotide exchange factors.

Gene - 7 Mar 2000

Trenkle T, McClelland M, Adlkofer K, Welsh J

Abstract excerpt

VAV3 is a new member of the VAV oncogene family with a strong homology to VAV and VAV2. A conceptual translation of the cDNA indicates that VAV3 is between 40 and 77% identical to VAV and VAV2 at the amino acid level in all identified functional motifs. This homology suggests that VAV3 occupies a similar position in signal transduction as the other family members. A major variant transcript, VAV3.1, found in both...

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Source

Identifiers

PMID: 10713454
DOI: 10.1016/s0378-1119(00)00026-3

Genes

VAV3
VAV2
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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