Article
C4B deficiency in two siblings with IgA nephropathy.
American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Jan 1990
Wyatt R J, Schneider P D, Alpers C E, Hudson E C, Julian B A
Abstract excerpt
The development of IgA nephropathy in first degree relatives is a well-described, yet relatively uncommon, occurrence. The association of a C4 isotype deficiency or partial deficiency of another complement protein has been previously documented for patients with IgA nephropathy. The present report describes a family in which two siblings and their father had biopsy-confirmed IgA nephropathy; both siblings were...
Topics
- Adolescent
- Adult
- Afibrinogenemia
- Complement C4a
- Complement C4b
- Electrophoresis, Agar Gel
- Female
- Glomerulonephritis, IGA
- Haplotypes
- Humans
- Male