Article
Regional variation in C4 phenotype in patients with IgA nephropathy.
The Journal of pediatrics - 1 May 1990
Wyatt R J, Rivas M L, Schena F P, Bin J A, Julian B A
Abstract excerpt
The relationship between complete deficiency for either isotype of the fourth component of complement, C4A or C4B, and glomerulonephritis was initially examined in white patients from Kentucky with either IgA nephropathy or Schönlein-Henoch purpura. Subsequently, C4B deficiency was found to be associated with IgA nephropathy for pediatric patients followed in Cincinnati, Ohio. We later reported that at least 60%...
Topics
- Adult
- Alleles
- Child
- Complement C4
- Complement C4a
- Complement C4b
- Gene Frequency
- Genetic Variation
- Glomerulonephritis, IGA
- Humans
- Italy
- Kentucky