Article
[High frequency of DQ8 in the celiac population of Chaco province, Argentina].
Acta gastroenterologica Latinoamericana - 1 Mar 2014
Motta Patricía Maria F, López María A, Marinic Karina, Picón Santiago O, Stafuza Mariana G, Habegger de Sorrentino Alicia
Abstract excerpt
BACKGROUND: There is a strong association between celiac disease (CD) and certain genes of the major histocompatibility complex (HLA). The CD specifically related alleles are those coding for HLA-DQ2 heterodimer and to a lesser degree for HLA-DQ8. OBJECTVE. The aim of this study was to evaluate the frequency of HLA-DQB1* and HLA-DRB1* alleles, haplotypes, and genotypes in patients diagnosed with CD and in control...
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