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Article

HLA-DQ typing in the diagnostic algorithm of celiac disease

1 May 2012

Abstract excerpt

OBJECTIVE: celiac disease (CD) is an immune-mediated chronic inflammatory disease associated with HLA-DQ2 and DQ8 molecules. We evaluated the role of HLA in the CD diagnostic algorithm in order to contribute to the development of practical indications for the use of HLA typing. MATERIAL AND METHODS: we selected 317 subjects typed for DR-DQ genes. CD was present in 123 patients, and 89 were included in the study;...

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PMID: 22662777
DOI: 10.4321/s1130-01082012000500005

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