Article
Frequency of HLA-DQ, susceptibility genotypes for celiac disease, in Brazilian newborns.
Molecular genetics & genomic medicine - 1 Sept 2018
Almeida Fernanda C, Gandolfi Lenora, Costa Karina N, Picanço Marilucia R A, Almeida Lucas M, Nóbrega Yanna K M, Pratesi Riccardo, Pratesi Claudia B, Selleski Nicole
Abstract excerpt
BACKGROUND: The frequency of HLA-DQ2 and DQ8 predisposing genotypes for celiac disease (CD) has shown significant variation among different world regions and has not been previously determined among the highly interbred Brazilian population. The aim of this study was to investigate the frequency of these genotypes among Brazilian newborns (NB). METHODS: We typed DQA1*05 - DQB1*02 (DQ2.5) and DQA1*03 - DQB1*03:02...
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