Article
Potent activation of RhoA by Galpha q and Gq-coupled receptors.
The Journal of biological chemistry - 26 Jul 2002
Chikumi Hiroki, Vázquez-Prado José, Servitja Joan-Marc, Miyazaki Hiroshi, Gutkind J Silvio
Abstract excerpt
Heterotrimeric G proteins of the G(i), G(s), and G(q) family control a wide array of physiological functions primarily by regulating the activity of key intracellular second messenger-generating systems. alpha subunits of the G(12) family, Galpha(12) and Galpha(13), however, can promote cellular responses that are independent of conventional second messengers but that result from the activation of small...
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