Article
Phenotypic change and proliferation of murine Kupffer cells by colony-stimulating factors.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Mar 1996
Hashimoto S, Yamada M, Yanai N, Kawashima T, Motoyoshi K
Abstract excerpt
Kupffer cells were isolated from C57BL/6 mice by collagenase perfusion and assessed for response to colony-stimulating factors (CSFs) in terms of their phenotypic change and proliferation. Kupffer cells expressed F4/80, but not Mac-1, CD71, or asialo-GM1 initially. This phenotype pattern was different from that of alveolar and peritoneal macrophages. After stimulation with recombinant human macrophage CSF (M-CSF)...
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