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Article

p53 status in multiple human urothelial cancers: assessment for clonality by the yeast p53 functional assay in combination with p53 immunohistochemistry.

Japanese journal of cancer research : Gann - 1 Feb 2000

Yamamoto S, Tada M, Lee C C, Masuda C, Wanibuchi H, Yoshimura R, Wada S, Yamamoto K, Kishimoto T, Fukushima S

Abstract excerpt

Multifocal synchronous or metachronous tumor development is a common observation in human urothelial cancer cases. However, the underlying mechanism has remained obscure. We have employed a new tool to investigate the p53 gene status, the yeast p53 functional assay, in combination with immunohistochemistry in a total of 50 tumor samples from 32 cases with urothelial cancers, including 8 with multiple synchronous...

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Identifiers

PMID: 10761705
DOI: 10.1111/j.1349-7006.2000.tb00930.x
PMCID: PMC5926329

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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