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Article

Conservation and diversification in homeodomain-DNA interactions: a comparative genetic analysis.

Proceedings of the National Academy of Sciences of the United States of America - 9 Jul 1996

Wilson D S, Sheng G, Jun S, Desplan C

Abstract excerpt

Nearly all metazoan homeodomains (HDs) possess DNA binding targets that are related by the presence of a TAAT sequence. We use an in vitro genetic DNA binding site selection assay to refine our understanding of the amino acid determinants for the recognition of the TAAT site. Superimposed upon the conserved ability of metazoan HDs to recognize a TAAT core is a difference in their preference for the bases that lie...

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Identifiers

PMID: 8692913
DOI: 10.1073/pnas.93.14.6886
PMCID: PMC38903

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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