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Article

Oxidative phenotype polymorphism (P450 2D6) and metabolism of toluene.

International journal of clinical pharmacology and therapeutics - 1 Jan 1996

Pelclová D, Mráz J, Patzelová V, Pícková J, Pospísil J, Vodicková L, Hornychová M, Vejlupková J

Abstract excerpt

Oxidative phenotype P-450 2D6 was examined using sparteine test in 3 groups of persons to determine if there is a coincidence in the defect of the oxidative biotransformation of sparteine and impaired oxidation of toluene, which could explain interindividual differences in the amounts of hippuric acid in the urine in exposed persons. The following groups of persons were examined: 30 rotogravure printers exposed...

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Share to Biotransformation
Share to Cytochrome P-450 CYP2D6

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Polymorphism, Genetic

Source

Identifiers

PMID: 8688995

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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