Article
Effects of ALDH2, CYP1A1, and CYP2E1 genetic polymorphisms and smoking and drinking habits on toluene metabolism in humans.
Toxicology and applied pharmacology - 1 Aug 1995
Kawamoto T, Koga M, Murata K, Matsuda S, Kodama Y
Abstract excerpt
In this study, we evaluated the effects of ALDH2, CYP1A1, and CYP2E1 genetic polymorphisms and smoking and drinking habits on the toluene metabolism. The study subjects were 92 male workers who handle toluene in a printing factory, an electrical parts factory, and a painting workplace in Japan. Their exposure levels to toluene were monitored using the diffusion-type sampler. Benzyl alcohol concentrations in their...
Topics
- Adult
- Aged
- Alcohol Drinking
- Aldehyde Dehydrogenase
- Base Sequence
- Benzyl Alcohol
- Benzyl Alcohols
- Creatinine
- Cytochrome P-450 CYP1A1
- Cytochrome P-450 Enzyme System
- Genotype