Article
[Association between CYP2B6, CYP2D6, GSTP1 genetic polymorphisms and urinary styrene metabolites in professional workers].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases - 1 Oct 2009
Wang Cui-Juan, Shao Hua, Shang Ming, Zhang Wei
Abstract excerpt
OBJECTIVE: To evaluate the influence of individual genetic polymorphisms of metabolic enzymes on urinary styrene metabolites. METHODS: 58 workers occupationally exposed to styrene were divided into the high exposure group (≥ 100 mg/m³) and the low exposure group (< 100 mg/m³). The microfluidic chip technology was used to determine the SNPs of CYP2B6, CYP2D6 and GSTP1 and the influence of gene polymorphisms on the...
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