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Article

Genetically determined sparteine oxidation and sulfadimidine acetylation polymorphism in patients with non-occupational urinary bladder cancer.

Materia medica Polona. Polish journal of medicine and pharmacy - 1 Jan 2000

Orzechowska-Juzwenko K, Niewiński P, Pawlik J, Milejski P, Dembowski J, Swiebodzki L, Lorenz J

Abstract excerpt

The results of our study revealed a predominance of the percentage of extensive metabolizers (EM) of sparteine (94.8%) among 58 patients with non-occupational urinary bladder cancer in comparison with the percentage of extensive metabolizers (91.2%) in healthy persons; the difference being not statistically significant. However, among ultrarapid (EM) oxidators with the metabolic ratio (MR) < 0.5 the difference in...

Topics

Acetylation
Adolescent
Adult
Aged
Female
Humans
Male
Middle Aged
Oxidation-Reduction
Phenotype
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sparteine

Sulfamethazine

Urinary Bladder Neoplasms

Source

Identifiers

PMID: 7666680

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7666680-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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