Article
Genetically determined sparteine oxidation and sulfadimidine acetylation polymorphism in patients with non-occupational urinary bladder cancer.
Materia medica Polona. Polish journal of medicine and pharmacy - 1 Jan 2000
Orzechowska-Juzwenko K, Niewiński P, Pawlik J, Milejski P, Dembowski J, Swiebodzki L, Lorenz J
Abstract excerpt
The results of our study revealed a predominance of the percentage of extensive metabolizers (EM) of sparteine (94.8%) among 58 patients with non-occupational urinary bladder cancer in comparison with the percentage of extensive metabolizers (91.2%) in healthy persons; the difference being not statistically significant. However, among ultrarapid (EM) oxidators with the metabolic ratio (MR) < 0.5 the difference in...
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